Meyler's Side Effects of Drugs

Parathyroid hormone and analogues

General information Both intact parathyroid hormone (e.g. PTH 1–34 , teriparatide) and smaller N-terminal fragments PTH 1–84 are used therapeutically. Recombinant PTH 1–34 is called teriparatide. No adverse reactions have been reported with single infusions of up to 60 mg…

Paraldehyde

General information Paraldehyde is the cyclic trimer of acetaldehyde, a colorless or slightly yellow-colored liquid. It has been used as an anticonvulsant, but because of adverse reactions and because it is difficult to use it has been replaced by more…

Paraffins

General information Paraffin is a name that is commonly used to denote a group of saturated alkane hydrocarbons with the general formula C n H 2n+2 , where “n” is greater than 20. They take both solid and liquid forms.…

Paracetamol (acetaminophen) and combinations

General information More than a century after its introduction, acetylsalicylic acid (aspirin) is by far the most commonly used analgesic, sharing its leading position with the relative newcomer paracetamol (acetaminophen), and notwithstanding the fact that other widely used compounds, such…

Parabens

General information Parabens (methyl, ethyl, propyl, and butyl esters of para-hydroxybenzoic acid) are used as preservatives in concentrations of 0.1–0.3% in pharmaceutical formulations and in concentrations of 0.01–0.1% in cosmetics and foods. In such concentrations they are devoid of systemic…

Papaverine

General information Papaverine is an alkaloid present in opium, but it is not related chemically or pharmacologically to other opium alkaloids. It has a direct relaxant effect on smooth muscle, partly attributable to inhibition of phosphodiesterase. Systemic adverse reactions reported…

Papaveretum

See also Opioid receptor agonists General information Papaveretum (Omnopon, Pantopon) is a mixture of several opium alkaloids. Organs and systems Urinary tract Renal insufficiency has been reported in a 60-year-old patient after the use of papaveretum for perioperative analgesia […

Papaveraceae

General information The genera in the family of Papaveraceae ( Table 1 ) include a variety of poppies and the greater celandine. Table 1 Genera of Papaveraceae Arctomecon (bear poppy) Glaucium (horn poppy) Platystigma (queen poppy) Argemone (prickly poppy) Hunnemannia…

Pantothenic acid derivatives

See also Vitamins General information The pantothenic acid derivatives include pantothenic acid, pantothenol, dexpanthenol, and hopantenic acid. Pantothenic acid (vitamin B 5 ) has been proposed as a treatment for hair loss. It has been used to treat pantothenic acid…

Pantoprazole

See also Proton pump inhibitors General information Pantoprazole is a proton pump inhibitor. Drug studies You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in…