General information Pegaptanib is a pegylated anti-VEGF aptamer, which is used to treat wet age-related macular degeneration and diabetic macular edema [ ]. Drug studies Observational studies Adverse reactions to intravitreal injection of pegaptanib (0.3, 1, or 3 mg every…
See also Fluoroquinolones General information Pefloxacin is a fluoroquinolone antibiotic that inhibits Plasmodium falciparum in vitro. It is effective against Plasmodium yoelii infections in mice. General adverse effects and adverse reactions The adverse effects of pefloxacin and reactions to it…
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See also Fluoroquinolones General information Pazufloxacin is an injectable quinolone antibiotic with bactericidal effect against cephalosporin-resistant, carbapenem-resistant, and aminoglycoside-resistant strains of bacteria. Organs and systems You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited…
See also Imatinib General information Pazopanib is a potent, selective, broad-spectrum, multi-targeted inhibitor of receptor tyrosine kinases, including VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-α/β, and c-kit. Total disease control in patients with advanced renal cell carcinoma was 82%. The most common adverse…
General information The family of Passifloraceae contains the single genus Passiflora incarnata , which contains over 500 species. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a…
General information Human parvovirus B19 is the causative agent of fifth disease, a rash-like disease of childhood, and in adults can cause arthralgia and chronic arthritis [ , ] and pure red cell aplasia [ ]. However, it has more…
See also Selective serotonin re-uptake inhibitors (SSRIs) General information Paroxetine is a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI). Pharmacokinetics The half-life of paroxetine is about 17–22 hours and about 95% of it is bound to plasma proteins.…
General information Parenteral nutrition should be tailored to the needs of the individual, but on average should provide about 25 kcal Solutions for long-term parenteral nutrition should contain: about 30% carbohydrate, usually in the form of glucose, providing 60% of…
See also COX-2 inhibitors (coxibs) General information Parecoxib sodium is an injectable COX-2 inhibitor developed for the treatment of acute pain. It is a prodrug of a sulfonamide-based COX-2 inhibitor, valdecoxib, a potent anti-inflammatory and analgesic drug. The published information…