See also Antiepileptic drugs ; Barbiturates ; Primidone General information Because it is cheap and of unquestioned efficacy, phenobarbital is still widely prescribed around the world, for both epilepsy [ ], including status epilepticus [ , ], and as an…
See also Anorectic drugs General information Phenmetrazine and phendimetrazine are central stimulants and indirect sympathomimetics related to dexamfetamine. Phendimetrazine is about 30% rapidly metabolized to phenmetrazine [ ]. Reported adverse reactions include glossitis, stomatitis, dry mouth, nausea, abdominal pain, cramps,…
See also Antihistamines General information Pheniramine is a first-generation antihistamine. Organs and systems You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
See also Antihistamines General information Phenindamine is an antihistamine that is reputed to cause stimulation rather than sedation in some patients. However, in one small study the central nervous system effects of phenindamine were intermediate between those of terfenadine and…
See also Monoamine oxidase inhibitors General information Phenelzine is a non-selective monoamine oxidase (MAO) inhibitor. Organs and systems Nervous system A potential risk of using a non-selective inhibitor in patients with Parkinson’s disease is illustrated by separate reports of the…
General information Phencyclidine or 1-(1-phenylcyclohexy-1) piperidine (known as PCP, “angel dust”, and many other names) was originally developed as an anesthetic, but was abused as an illicit drug from the late 1960s onwards. It is a dopamine receptor agonist and…
General information Phenazopyridine, an azo dye, is used as a urinary tract analgesic. Although its use is not justified, because of toxicity, and although it was, for example, withdrawn in Greece in 1984, it continues to be used [ ,…
General information Phenazone, commonly known as antipyrine, is still used therapeutically in some countries, although it is now used mainly as a marker of hepatic enzyme drug metabolizing activity. It is usually taken in combination with other analgesics, making attributability…
See also Opioid receptor agonists General information Pethidine (meperidine) is about one-tenth as potent as morphine in terms of analgesia. It is metabolized in the liver by hydrolysis and conjugation, either directly or via N-demethylation to norpethidine. Norpethidine (normeperidine) is…
See also Vaccines General information Note on abbreviations DT = Diphtheria + tetanus toxoids DTP = Diphtheria + tetanus toxoids + pertussis DTaP = Diphtheria + tetanus toxoids + acellular pertussis DTwP = Diphtheria + tetanus toxoids + whole cell…