General information Piretanide is structurally related to furosemide, with diuretic and kinetic properties very similar to those of furosemide and bumetanide [ ]. Its potency lies somewhere between the two. As with some other diuretics, attempts have been made to…
General information Pirenzepine is an anticholinergic drug with selective effects on muscarinic M 1 receptors, although there is also evidence that it can be an antagonist at M 2 receptors as well. It inhibits gastric acid secretion in the stomach,…
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General information Piracetam is a so-called “nootropic” drug, one of a class of drugs that affect mental function [ ]. In healthy volunteers it improves the higher functions of the brain involved in cognitive processes, such as learning and memory.…
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General information Piperazine is an antihelminthic drug that selectively blocks the neuromuscular cholinergic receptors of worms. It is readily absorbed, but has a highly variable half-life. The adult oral dose of 4 g of piperazine hydrate has been used extensively…
General information Piperaquine is a synthetic 4-aminoquinoline with high blood schizonticidal activity, similar to that of chloroquine [ ]. It was developed in the 1960s by Shanghai Pharmaceutical Industry Research (China) and Rhone Poulenc (France) and has been combined with…
General information The family of Piperaceae contains three genera: 1. Lepianthes (lepianthes) 2. Peperomia (peperomia) 3. Piper (pepper) Piper methysticum Kava or awa ( Piper methysticum ) is a plant that grows in the South Pacific Islands. Eight species have…
General information Pipecuronium bromide is a bisquaternary steroid analogue of pancuronium. In vitro pipecuronium reversibly inhibits both human red cell acetylcholinesterase and human plasma cholinesterase to an extent that might have clinical implications [ ]. Its potency is similar to…
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