General information Plasma products are used to substitute plasma proteins and in plasma exchange. Fresh frozen plasma is used as a source of coagulation factors in deficiency, if no purified factors are available. Intensive plasma exchange has been studied in…
General information The family of Plantaginaceae contains two genera: 1. Littorella (littorella) 2. Plantago (plantain) You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in…
General information Plague vaccine is a suspension of the formaldehyde-killed encapsulated form of Yersinia pestis . Primary immunization involves three doses given intramuscularly. The Working Group on Civilian Biodefense has developed consensus-based recommendations for measures to be taken by medical…
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See also Antihistamines General information Pizotifen is a 5HT receptor antagonist chemically related to the tricyclic antidepressants, with a five-membered third ring containing a sulfur atom. It has been suggested that adverse reactions to pizotifen resemble those of amitriptyline […
See also Non-steroidal anti-inflammatory drugs (NSAIDs) General information Pirprofen is a non-steroidal anti-inflammatory drug, a phenylpropionic acid derivative. It has been used to treat rheumatoid arthritis [ ], osteoarthritis [ ], and ankylosing spondylitis [ , ], and as an…
General information Piroxicam was the first of the oxicam compounds, and is by far the most widely used. It is an inhibitor of prostaglandin synthesis and platelet aggregation. Its long half-life (36–48 hours) allows it to be given in a…
General information Piritrexim is a lipid-soluble analogue of methotrexate that has been used to treat methotrexate-resistant tumors [ ], including recurrent and metastatic head and neck cancers [ ], soft-tissue sarcomas [ ], non-small cell lung cancers [ ], metastatic…
General information Piridoxilate, an equimolar mixture of glyoxylic acid and pyridoxine, is marketed in a few countries (for example France) for peripheral arterial occlusive disease and functional venous disorders [ ], including vascular ulcers [ , ]. The supposed rationale…
General information Piribedil is a piperazine derivative, a non-ergot dopamine receptor agonist, whose pharmacology is unusual, in that it is an agonist at D 2 and D 3 receptors and an α 2 -adrenoceptor agonist. It has been used for…