See also Individual agents General information The postsynaptic alpha-adrenoceptor antagonists, indoramin, prazosin, and related quinazoline derivatives, block alpha1-adrenoceptor-mediated vasoconstriction of peripheral blood vessels (both arterial and venous) and are effectively peripheral vasodilators [ , ]. Qualitatively and quantitatively common adverse…
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General information Alpha 1 -antitrypsin is an alpha 1 proteinase inhibitor that neutralizes the activity of neutrophil elastase and is used to treat patients with homozygous deficiency of alpha 1 -antitrypsin [ ]. Adverse reactions occur only rarely [ ].…
See also Ondansetron and other 5HT 3 receptor antagonists Drug studies Placebo-controlled studies In a 12-week placebo-controlled study of alosetron 0.5 mg/day, 1 mg/day, or 1 mg bd in 705 women with severe diarrhea-predominant irritable bowel syndrome, all doses of…
General information The family of Aloeaceae contains the single genus Aloe . Aloe capensis and Aloe vera Aloe capensis and Aloe vera ( Aloe barbadensis ) (Barbados aloe, burn plant, Curacao aloe, elephant’s gall, first-aid plant, Hsiang dan, lily of…
General information Almitrine is a respiratory stimulant that improves hypoxemia in about 80% of patients with severe chronic obstructive pulmonary disease [ ]. Oral almitrine bimesilate (100 mg/day) increased PaO 2 in patients with severe chronic obstructive pulmonary disease without…
General information Allopurinol is an inhibitor of xanthine oxidase, used to lower serum uric acid concentrations in the long-term treatment of gout and in the prevention of acute gout in people who are susceptible to hyperuricemia. Allopurinol is itself metabolized…
See also Cytotoxic and immunosuppressant drugs General information Alkylating cytostatic drugs include: Nitrosoureas: carmustine, lomustine, nimustine, streptozocin. N -lost derivatives: bendamustine, chlormethine, cyclophosphamide, estramustine. Others: busulfan, chlorambucil, dacarbazine, ifosfamide, melphalan, mitobronitol, mitomycin, procarbazine, thiotepa, temozolomide, treosulfan. The first two groups…
General information Alizapride is a substituted benzamide related to some neuroleptic drugs. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
See also Renin inhibitors, direct General information Aliskiren is an orally active, non-peptidic inhibitor of renin, and is the only direct renin inhibitor approved for the treatment of hypertension. Its potential adverse effects and a comparison with other renin–angiotensin blockers…