General information Angiotensin-converting enzyme (ACE) inhibitors inhibit the conversion of angiotensin I to angiotensin II ( Figure 1 ). The ACE is also a kininase, and so ACE inhibitors inhibit the breakdown of kinins. Some of the adverse effects of…
See also individual agents General information Inhibition of the renin–angiotensin system by ACE inhibitors has proved efficacious in the treatment of hypertension, cardiac failure, myocardial infarction, in secondary prevention after myocardial infarction, and for kidney protection in diabetic and non-diabetic…
See also individual agents General information Local anesthetics typically contain a hydrophilic tertiary amine group linked to a lipophilic ester or amide. The most commonly used local anesthetics are either amides or esters, as shown in Table 1 . The…
General information The inhalational and injectable agents that are covered in separate monographs are listed in Table 1 . Table 1 Inhalational and injectable anesthetics Inhalational Injectable Halogenated Chloroform Desflurane Enflurane Halothane Isoflurane Methoxyflurane Sevoflurane Trichloroethylene Others Anesthetic ether Cyclopropane…
You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
General information Anecortave acetate is an angiostatic steroid derived from cortisol but without glucocorticoid receptor-mediated activity. It has been used in the treatment of neovascularization in age-related macular degeneration [ , ] and in glaucoma [ ]. It tends to…
See also Hormonal contraceptives—male General information The classic androgen is natural testosterone, which can be given orally in micronized form, but has much more often been used as the orally active 17-methyl derivative or an injectable ester. Androgens are used…
See also Interleukins General information Anakinra is an interleukin-1 receptor antagonist. It has been used to treat rheumatoid arthritis [ , ]. It has been tried in graft-versus-host disease, but without success [ ]. According to published trial data, moderate…
General information Anagrelide was developed as an inhibitor of platelet aggregation and acts by inhibiting phosphodiesterase. It was later found to reduce the platelet count, in doses lower than those required to inhibit platelet aggregation, by interfering with megakaryocyte differentiation…
See also Herbal medicines General information Genera in the family of Anacardiaceae ( Table 1 ) include pistachio, poison ivy, and sumac. Many yield foodstuffs, such as mangos, cashews, and pistachios, that can cause allergic reactions. Table 1 Genera of…