Handbook of Dialysis Therapy

Peritoneal Dialysis in Neonates and Infants

Introduction Peritoneal dialysis (PD) has long been considered an effective treatment modality for neonates and infants with severe acute kidney injury (AKI) and is the dialysis modality of choice for patients in this age group with end-stage kidney disease (ESKD).…

Nutritional Management of Children Undergoing Peritoneal Dialysis

Nutritional management is a key component of the care of children treated with peritoneal dialysis (PD). This includes regular assessment of nutritional status as well as development and implementation of a dietary prescription. Optimal nutritional management requires collaboration among the…

Prescribing Peritoneal Dialysis in Children

Peritoneal dialysis (PD) became a more available therapy for children in the 1960s, such that it was no longer considered “experimental” by the early 1970s. Further advances have been made in the size of catheters and tubing and the technology…

Urea Kinetic Modeling for Hemodialysis Prescription in Children

Chronic Hemodialysis in Children Although renal transplantation is the optimal treatment for end-stage kidney disease in children and adolescents, many pediatric patients nonetheless must spend some time on chronic dialysis. Historically, a much larger proportion of children than adults undergo…

Infant Hemodialysis

Vascular Access Hemodialysis requires a central venous catheter, and in infants, this poses technical challenges because of their smaller vessel size and the likelihood that they may require vascular access throughout their lifetime if end-stage renal disease is present. Dialysis…

Treatment of Poisoning with Extracorporeal Methods

More than 2 million poisonings were reported to the American Association of Poison Control Centers in 2021. Outcomes are generally favorable, and supportive measures alone are sufficient to manage the majority of poisonings. In selected situations, gastrointestinal decontamination, timely administration…

Anticoagulation for Continuous Renal Replacement Therapy

Continuous renal replacement therapy (CRRT) has evolved as the preferred form of dialysis in hemodynamically unstable critically ill patients with acute kidney injury (AKI). It is applied continuously and achieves solute clearance and fluid removal by convection, as in continuous…