Goldman-Cecil Medicine

Shigellosis

Definition Shigellosis results from inflammation of the large intestine due to infection with bacteria of the genus Shigella . Clinical presentation is either with acute watery diarrhea or bloody diarrhea, known as dysentery, and is commonly accompanied by fever. Shigellosis…

Salmonella Infections (Including Enteric Fever)

Definition Many of the more than 2500 serovars (also called serotypes) of Salmonella enterica subspecies enterica infect humans and cause a range of clinical conditions from asymptomatic intestinal carriage to intestinal infection to invasive disease with extraintestinal complications. Each serovar…

Diseases Caused by Acinetobacter and Stenotrophomonas Species

Acinetobacter Spp Definition The Pathogen Acinetobacter spp are gram-negative, aerobic, coccobacillary bacteria, which are generally non–lactose-fermenting, nonfastidious, catalase positive, oxidase negative, and nonmotile, though their description of being “nonmotile” is questioned. The Gram stain appearance of Acinetobacter spp is highly…

Pseudomonas and Burkholderia Infections

Pseudomonas Infection Definition Infections due to Pseudomonas spp are caused by members of the family Pseudomonadaceae. The Pseudomonadaceae is a group of gram-negative rods, including P. aeruginosa , the most frequently recovered human pathogen in the family. Other Pseudomonas s…

Escherichia Coli Enteric Infections

Definition Bacteria belonging to the species Escherichia coli are a normal component of the intestinal microbiota ( Chapter 257 ). The majority of E. coli are harmless commensals, but specific isolates have acquired pathogenicity genes that enable them to cause…

Campylobacter Infections

Definition Campylobacter jejuni is one of the most commonly recognized bacterial causes of diarrhea in developed and underresourced nations. More than 95% of campylobacter isolated in developed countries are C. jejuni or C. coli . However, other Campylobacter species are…

Cholera and Other Vibrio Infections

Cholera Definition Cholera is a dreaded epidemic diarrheal disease caused by Vibrio cholerae serogroup O1 and, since 1992, by the new serogroup O139. The disease is characterized by acute, large-volume watery diarrhea. In its more severe form, a person may…

Haemophilus and Moraxella Infections

Haemophilus Influenzae Definition Haemophilus refers to the bacteria’s requirement for specific blood components for growth. In the respiratory tract, which is the primary site of colonization for most Haemophilus species, the most common infections include otitis media, sinusitis, bronchitis, and…

Chancroid

Definition Chancroid is a sexually transmitted disease that is characterized by painful genital ulcers and inguinal lymphadenitis caused by Haemophilus ducreyi . H. ducreyi also is a major cause of nonsexually transmitted cutaneous ulcers in children who live in regions…