Uses Prevention of pregnancy Treatment of the following: Dysmenorrhea Menorrhagia/iron-deficiency anemia Acne Endometriosis Functional ovarian cyst Hyperandrogenism and/or polycystic ovarian disease Premenstrual syndrome and/or premenstrual dysphoric disorder Perimenopausal vasomotor symptoms Mittelschmerz Perioperative Risks Hypercoagulability; increased risk of venous and arterial…
Risk Up to 40% of pts may be undernourished on admission to hospital, and two-thirds of all pts lose weight during hospital stay. 60% of elderly pts are malnourished at discharge. More than 376,000 people depend on TPN per year…
Uses Incidence in USA: 100 million prescriptions are written per year; 17 million Americans use NSAIDs daily. Have analgesic, anti-inflammatory, and antipyretic properties. NSAIDs are the first step in the analgesic ladder of WHO; typically considered drugs of choice for…
Uses Primary indications include Hyperlipidemia: Hydroxymethylglutaryl coenzyme-A (HMG-CoA) reductase inhibitors (statins) are the major hypolipidemic drugs. Nonstatin drugs are used in pts with side-effects or those not responding well to statin therapy. Evolocumab also has an indication specifically for the…
Uses Therapy for pts with angina. CHF In MI, can reduce infarct size. Prinzmetal angina. Can be given as a patch, paste, or pill taken sublingually as needed. Uterine relaxation for retained placenta, although a systematic review did not demonstrate…
Uses Children: Acute or chronic pulm Htn associated with persistent pulmonary Htn of newborn (PPHN), meconium aspiration, CHD, and congenital diaphragmatic hernia Adults: Acute or pulm Htn associated with ARDS, pulm embolism, placement of a LVAD, and cardiac surgery Perioperative…
Acknowledgment The author would like to acknowledge the contributions of Drs. Subramanian Sathishkumar and Sanjib Adhikary to this chapter in the previous edition. Uses NRTs are USA FDA-approved devices that are effective in helping treat tobacco dependence, acting on nicotinic…
Uses Reverse the effects of opioid-agonist overdose (although IV therapy is preferred). Prevent relapse in pts (including physicians) addicted to alcohol and/or opioids. Oral route is most common and popular. Newer formulations (e.g., Vivitrol [naltrexone for extended-release injectable suspension]) are…
Uses MAOIs are a broad class of psychoactive medications that affect the metabolism of multiple neurotransmitters. MAOIs are indicated for many psychiatric conditions including but not limited to atypical depression, refractory depression, depression with prominent anxiety, low psychomotor activity, and…
Uses Treatment of type 2 DM, particularly in overweight pts, when dietary management and exercise alone do not result in adequate glycemic control. A reduction of diabetic complications has been shown in overweight type 2 diabetic pts treated with metformin…