Essence of Anesthesia Practice

Procainamide (Procan, Procanbid, Pronestyl)

Uses Treats recurrent or sustained hemodynamically stable monomorphic VT (IIa/C)/(IIa/C). ∗ ∗ The first number and lowercase letter refer to the ACC/AHA system of classifying guidelines while the uppercase letter refers to the level of evidence. Not indicated for asymptomatic…

Physostigmine, Eserine

Uses Central anticholinergia; used for diagnosis and treatment in patients with a Hx of anticholinergic ingestion and/or exposure: Atropine, scopolamine, belladonna, jimson weed, toxic mushrooms, tricyclics, phenothiazines, antihistamines, benzodiazepines, opiates, inhalation anesthetics, propofol, GHB. “Blind as a bat”: Mydriasis and…

Phenytoin

Uses Management of generalized tonic-clonic (grand mal) and complex partial seizures Prophylaxis against seizures after trauma or surgical intervention Treatment of ventricular arrhythmias, especially those associated with digitalis or tricyclic antidepressant toxicity Treatment of prolonged QT interval Treatment of epidermolysis…

Phenylephrine (Neo-Synephrine)

Uses Prescribed mainly as nasal decongestant or ophthalmically for treatment of mydriasis, capillary decongestion. Reliable vasopressor in treatment of hypotension. Used in obstetric anesthesia for hypotension after spinal. More effective as a prophylactic infusion than bolus doses. Prolongs local anesthetic…

Phenoxybenzamine

Uses Incidence in USA: 3600 per y Rx for preop pheochromocytoma; occasionally for chronic Rx of pheochromocytoma and sympathetic hyperactivity states, carcinoid syndrome, BPH Perioperative Risks Drug interactions: Sometimes requires very high doses of α-adrenergic agents to produce vasoconstriction. Vasodilation,…

Phenothiazines

Uses Phenothiazine compounds are clinically useful antipsychotic and antiemetic medications. Phenothiazine antihistamines such as promethazine (phenergan) and prochlorperazine (compazine) are highly effective antiemetics. Phenothiazine neuroleptics such as chlorpromazine (thorazine) are used in the treatment of schizophrenia and psychosis. Chlorpromazine can…

Phencyclidine

Uses DEA Schedule I drug of abuse with no present medical indications; street terms for PCP include angel dust, supergrass, killer weed, embalming fluid, rocket fuel, wack, and ozone. Common routes of administration: Smoking (often laced in marijuana cigarettes), oral…

Penicillins

Uses Prescribed for pts with infections due to sensitive organisms, primarily Pneumococcus and those in genera Streptococcus , Staphylococcus , Neisseria , Pseudomonas , Proteus , Haemophilus , Helicobacter , Moraxella, and so on; used as prophylaxis for subacute bacterial…

P2Y 12 Receptor Blockers

Uses P2Y 12 RBs used alone or in combination with ASA (DAPT). ACS, those undergoing PCI with stent placement, and pts with NSTEMI or STEMI. Continue for 6–12 mo after insertion of drug-eluting stent (DES), and 4–6 wk after insertion…

Oral Hypoglycemic Agents

Uses Oral hypoglycemic agents are used to manage type 2 diabetes mellitus. The term oral hypoglycemic agents is becoming obsolete and is being replaced by the term noninsulin glucose-lowering drugs because the glucagon-like peptide 1 analogues are injected. You’re Reading…