Risk 1:15,000-50,000 live births Most common human chromosomal syndrome Perioperative Risks Difficult airway management due to anatomic abnormalities of the airways. 30% can present with congenital heart disease. Aspiration risk. May require temp control. Cardiac events (pts may have cardiac…
Risk Iatrogenic transmission (actual and theoretical) Blood products: blood transfusion (3 reported cases). Greater risk with pooled products (since 1999 UK has imported blood fractions) or massive blood transfusion. Risk mitigated by deferral of recipients as donors (initiated: 1998 in…
Risk Pts with Hx of exposure to silica dust or PVC. Usual age group is 30–50 y. Fourfold to ninefold higher incidence in women than men; seen in all races. In USA systemic sclerosis has an estimated incidence of 19…
Risk Occurs in 1:2000-2500 live births. May be spontaneous, syndromic, or familial, but it most commonly presents as an isolated abnormality; however, it can present as a component of a syndrome or genetic disorder in 15–40% of pts. Familiarity with…
Risk Cleft lip and palates are the most common birth defects in USA. Cleft lip and/or palate incidence in USA is 1:600 newborns. Craniofacial clefts are rare, with incidence of 1:1000 births worldwide. Increased prevalence with Asians, Latinos, and Native…
Risk Disease affecting mostly middle- and old-aged men and postmenopausal women Gender difference: Higher incidence in women Periop CAS: Prevalent in elderly male pts with coronary risk factors Teenagers and young adults with illicit substance abuse, primarily cocaine Occurs in…
Risk Incidence in USA: 15.5 million. Approximately 735,000 pts per y with CAD will have an acute MI and approximately 15% of these will die. CAD is responsible for approximately 1 of every 7 deaths in USA. Male predominance in…
Risk RV failure is the third most common cardiac Dx after age 50 y. Of all CHF admissions, 10–20% have some aspect of right heart failure. Gender predominance is male > female. Perioperative Risks Increased risk for respiratory failure, severe…
Risk Reported prevalence varies widely (11–500”100,000). It may account for unexplained symptoms in as much as 1–14% of general medical/surgical pts and possibly as much as 20% of new outpatient neurology referrals. Possibly higher in rural populations, developing areas, lower…
Risk Median prevalence of constipation in adults is 16% (studies range 0.7–79%); in adults aged ≥60 y, it is 33.5%. Prevalence may be higher in nonwhite and institutionalized populations. Male:female ratio: 1:1.5. Perioperative Risks Increased risk of gastroparesis and N/V…