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List of abbreviations 2-DG 2-Deoxyglucose 2-FDG 2-Fludeoxyglucose 3D Three direct-acting antivirals ABC7 Adjuvant for breast cancer treatment using seven repurposed drugs ABCG2 ATP-binding cassette superfamily G member 2 ADH Alcohol dehydrogenase ADRB Adrenoreceptor beta ALDH Aldehyde dehydrogenase AMP Adenosine monophosphate…
List of abbreviations ABPP Activity-based protein profiling ADR Adverse drug reactions AI Artificial intelligence AML Acute myeloid leukemia ANN Artificial neural networks ATC Anatomical therapeutic classification AUC Area under curve AUROC Area under the receiver operating characteristic curve BBB Brain–blood…
Introduction The 2018 Nobel Prize in Physiology or Medicine was awarded to two researchers for their discovery of immune checkpoint proteins [ ]. Although the discovery initiated the development of the revolutionary targeted immunotherapies, critical challenges remain to be addressed,…
Acknowledgments The authors are thankful to OpenEye Scientific Software, Santa Fe, NM, USA, for providing access to free academic evaluation license. SC acknowledges the financial support by Department of Science and Technology, Government of India toward her research through DST-INSPIRE…
Acknowledgments The authors wish to thank Andrea Leurs, KU Leuven, for assistance with the preparation of the data on drug repurposing clinical trials. Introduction It incumbent upon us to seek new therapeutic options for cancer patients wherever they may be…