Synonyms ▪ Cutaneous B-cell lymphomas ▪ S kin- a ssociated l ymphoid t issue (SALT)-related B-cell lymphomas Key features ▪ Cutaneous B-cell lymphomas represent a group of lymphomas whose primary site is the skin; they are derived from B lymphocytes…
Key features ▪ Mastocytosis can develop from birth to adulthood and may involve only the skin (most children and some adults) or multiple organs such as the bone marrow, liver, spleen, and/or lymph nodes (primarily adults) ▪ Childhood disease is…
Introduction Smooth muscle, adipose and cartilage neoplasms arising in the skin and subcutis comprise a wide spectrum of benign and malignant neoplasms that show myocyte, adipocyte, and chondrocyte differentiation, respectively. Tumors of fat, especially lipomas, occur most commonly. These neoplasms…
Key features ▪ Fibrous and fibrohistiocytic proliferations of the skin and tendons are common lesions that include both neoplastic and “reactive” processes ▪ Common benign fibrous and fibrohistiocytic proliferations, some of their atypical variants that could be misdiagnosed as malignant…
In the past, neural tumors were often misdiagnosed histopathologically because of confusing classifications. As a result, their clinical relevance was poorly understood. Clinically, cutaneous neural tumors often look alike and most of them are benign. However, their correct diagnosis can…
Introduction In this chapter we use the term neoplasm synonymously with tumor in a general, albeit imperfect , sense, consistent with its common usage: an abnormal proliferation (“new growth”) of cells that appears to be relatively autonomous (i.e. not reactive)…
Key features ▪ Melanoma represents a malignant tumor that arises from melanocytes, and, due to its metastatic potential, leads to >90% of skin cancer deaths ▪ The incidence rates of melanoma have increased over the past four decades by five-…
Ephelides Synonym ▪ Freckles Key features ▪ Small, well-circumscribed, pigmented macules found only on sun-exposed skin of individuals with fair skin Epidemiology and Pathogenesis Ephelides are common in individuals with blond or red hair . They are not present at…
Key features ■ Terminology and classification of adnexal tumors has varied considerably according to different authorities ■ Adnexal neoplasms can differentiate toward the folliculosebaceous-apocrine unit or the eccrine apparatus ■ As a reflection of joint ontogeny, tumors often exhibit combinations…
Key features ▪ Multiple types of cutaneous cysts have been described ▪ Cutaneous cysts present as circumscribed dermal or subcutaneous papules or nodules ▪ Histologic features of the cyst lining and the anatomic location determine the type of cyst ▪…