Complications in Anesthesia

Local Anesthetic Systemic Toxicity

Case Synopsis A 76-year-old man (184 cm, 58 kg, American Society of Anesthesiologists [ASA] status 3) was scheduled for a total shoulder arthroplasty. His medical history was significant for coronary artery disease with remote bare metal stent placement and atrial…

Epidural Anesthesia : Unintended Intrathecal Injection

Case Synopsis A frail, 55-kg, 79-year-old woman is admitted for elective hip replacement as the first surgery of the day in a specialty orthopedic surgery center. An epidural catheter is placed for surgical anesthesia and postoperative analgesia. With the patient…

Blood and Blood Products : Transfusion Reactions and Complications

Case Synopsis A 33-year-old woman, G3P2002 at 34 weeks’ gestation with a known history of placenta previa, undergoes ultrasound concerning for placenta accreta. The patient underwent a successful cesarean section under epidural anesthesia but required allogeneic blood transfusions that included…

Blood and Blood Products : Infections

Case Synopsis A 70-year-old man with a history of coronary artery disease and a new diagnosis of abdominal aortic aneurysm is being evaluated in the preoperative area for an open repair. His hemoglobin is 10 g/dL, and you decide to…

Volatile Anesthetics : Organ Toxicity

Case Synopsis A 53-year-old woman has laser excision of vocal cord papillomas under anesthesia with halothane and spontaneous ventilation. She has had several prior excisions, including one a month earlier, all with halothane; all were uneventful. However, 1 week after…

Succinylcholine

Case Synopsis A 52-year-old woman with bipolar depression undergoes her first electroconvulsive therapy (ECT) treatment. Past history is otherwise pertinent only for hemiparetic, static encephalopathy as a result of meningitis in infancy and hypertension. Medications include lamotrigine, lurasidone, and lisinopril.…

Reversal Agents : Naloxone, Flumazenil, and Sugammadex

Naloxone Case Synopsis An otherwise healthy 65-year-old, 80-kg man is given 2 mg of fentanyl intravenously (IV) during a 3-hour coronary artery bypass grafting procedure. Postoperatively, the patient remains intubated and mechanically ventilated and is transferred to the intensive care…

Perioperative Fluid Management

Case Synopses Case 1 A 72-year-old man is scheduled to undergo transverse colectomy and primary reanastomosis for a nonobstructing carcinoma. He has a history of hypertension that is well controlled by a diuretic and is otherwise healthy. Case 2 A…

Nondepolarizing Neuromuscular Block

Case Synopsis Following emergence and tracheal extubation after general anesthesia with neuromuscular relaxation, a 52-year-old woman with a history of chronic renal insufficiency has labored breathing with paradoxic movement of the chest wall and abdomen and intermittent upper airway obstruction.…

Nonbarbiturate Anesthetics

Case Synopsis A 53-year-old, 75-kg man with a past medical history significant for poorly controlled hypertension and non–insulin-dependent diabetes is scheduled for an external fixation of a femur fracture sustained after a fall off a ladder 2 days ago. The…