Introduction The treatment of advanced and recurrent colorectal cancer represents a significant challenge to oncologists and surgeons, requiring a multimodality treatment approach. As a result, the National Institute for Health and Care Excellence (NICE; 2020) colorectal cancer guideline recommends these…
Acknowledgement This chapter in the sixth edition was written by Simon Gollins and David Sebag-Montefiore and we are grateful to them for those parts of the chapter, which we have kept in this edition. Introduction Colorectal cancer is the fourth…
Introduction Rectal cancer is defined as adenocarcinoma within 15 cm of the anal verge, and accounts for around 30% of colorectal cancers. There were 14 555 cases of rectal cancer in 2017 in the UK. Surgical excision remains the primary…
Acknowledgement The authors and editors would like to thank Jordan Fletcher for developing and providing the illustrations for this chapter. Introduction The principles of surgery for colon cancer have been unchallenged for decades, and include a sufficient longitudinal resection margin,…
Introduction Individuals develop colorectal cancer (CRC) as a result of interaction between their genotype and the environment to which they are exposed. The lifetime risk of CRC in the UK population is about 5%. As it is common, many people…
Acknowledgement This chapter in the sixth edition was written by Robert Steele and I am grateful to him for those parts of the chapter, which we have kept in this edition. Introduction Colorectal cancer is a significant healthcare issue in…
Introduction Since flexible endoscopy of the colon was introduced in 1963, it has become the gold-standard diagnostic test for evaluation of colonic disease. Improvements in technique and technology have also led to advances in therapeutic procedures, and the boundary between…