Bradley and Daroff's Neurology in Clinical Practice

Lower Back and Lower Limb Pain

Lower back pain is one of the most common reasons for neurological and neurosurgical consultation. In many of the patients who present with lower back pain, the pain either developed or was exacerbated as a result of occupational activity. Lower…

Arm and Neck Pain

Evaluation of the patient with arm and/or neck pain is based on a meticulous history and clinical examination. A useful approach is to consider the diagnosis in terms of pain-sensitive structures in the neck and upper limbs. These structures may…

Sensory Abnormalities of the Limbs, Trunk, and Face

Clinical evaluation of sensory deficits is inherently more difficult than evaluation of motor deficits because of the subjective nature of the examination. Nevertheless, it is important to identify sensory deficits in order to localize lesions. Anatomy and Physiology Peripheral Pathways…

Hypotonic (Floppy) Infant

A floppy, or hypotonic, infant is a common scenario encountered in the clinical practice of child neurology. It can present significant challenges in terms of localization and is associated with an extensive differential diagnosis ( Box 30.1 ). As with…

Muscle Pain and Cramps

General Features of Pain Pain is an uncomfortable sensation with sensory and emotional components. Short episodes of pain or discomfort localized to muscle are a near universal experience. Common causes of short-term muscle discomfort are unaccustomed exercise, trauma, cramps, and…

Proximal, Distal, and Generalized Weakness

Muscle weakness may be due to disorders of the central nervous system (CNS) or peripheral nervous system (PNS). The PNS includes the primary sensory neurons in the dorsal root ganglia, nerve roots, peripheral nerves, neuromuscular junctions, and muscles. Although not…

Paraplegia and Spinal Cord Syndromes

Paraplegia and quadriplegia may result from a variety of systemic and primary central nervous system medical conditions as well as trauma at all segmental levels of the spinal cord ( Box 27.1 ). A spinal cord syndrome may develop from…

Hemiplegia and Monoplegia

Hemiplegia and monoplegia are more likely to be due to discrete focal lesions than diffuse lesions, so these presentations are especially suited to clinical-anatomical localization. Similarly, imaging studies are likely to be revealing with hemiplegia or monoplegia, but the focus…

Gait Disorders

The maintenance of an upright posture and the act of walking are among the first and ultimately most complex motor skills humans acquire. From an early age, walking skills are modified and refined. In later years, the interplay between voluntary…