Atopic Dermatitis: Inside Out or Outside In

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Complementary and Alternative Approaches II

Key points A review of a variety of alternative therapies for atopic dermatitis (AD) is the focus of this chapter. Among those reviewed are acupuncture, cupping, and herbal therapies, which are common traditional Chinese therapies used by AD patients. We…

Complementary and Alternative Approaches I

Key points Current first-line conventional treatments for atopic dermatitis include topical corticosteroids, emollients, and topical and/or systemic immunomodulators (e.g., dupilumab). However, a majority of patients with atopic dermatitis are interested in or have tried complementary and alternative medicine (CAM) approaches.…

Itch and Pain Treatments

Key points Itch and pain are key symptoms of atopic dermatitis (AD) that significantly affect quality of life; various classes of treatment aim to reduce these symptoms. Nonpharmacologic and topical therapies are effective for mild or moderate itch or pain…

Microbiome Modulation

Key points The use of probiotics to promote a healthy state has been widely studied. Oral probiotics have been shown to aid in the prevention of atopic dermatitis in select populations. Oral probiotics may also help in the treatment of…

Emerging Targeted Treatments

Key points This chapter provides an overview of the pathogenesis of atopic dermatitis and the key mediators that are of therapeutic interest. As we acquire more knowledge into the pathogenesis of atopic dermatitis, we will be able to use more…

Skin Barrier Repair

Key points Moisturizers help with skin barrier repair and continue to be the mainstay of maintenance treatment and prevention of flares in atopic dermatitis (AD). Though greasier moisturizer delivery systems such as ointments and creams are most effective, patient compliance…

Wound Care

Key points Issues with wound healing in patients with atopic dermatitis (AD) relate to innate inability to repair the barrier, defective angiogenesis, abnormal microbial colonization, and a prolonged inflammatory phase. Patients with AD are at a higher risk for hypersensitivity…

Topical Therapies

Key points Optimal bathing practices can improve atopic dermatitis (AD) symptoms and limit disease flares. Best practices include daily bathing for less than 10 minutes in lukewarm water, utilizing neutral to mildly acidic nonsoap cleansers, and the immediate application of…

Therapeutic Guideline Overview

Key points Multiple clinical guidelines, consensus statements, and expert management recommendations have been published for atopic dermatitis. Most prominent guidelines are from the American Academy of Dermatology and the College of Allergy, Asthma & Immunology Joint Task published in 2014…