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Assessing the risk posed by pregnancy, for both the mother and baby, is an essential component of caring for women with cardiac disease who are considering becoming pregnant as well as for those who are already pregnant. This chapter explores both maternal and fetal risk assessment.
Whenever possible, risk stratification should occur antenatally, and for women at high risk, who have a lesion that can be corrected, intervention should be performed before they become pregnant. There are many factors known to increase risk in cardiac patients who become pregnant, and ideally, patients have been apprised of the risks before they conceive. Regardless of whether this has been discussed previously with patients, we perform a risk stratification at intake.
A number of factors should be considered when attempting to estimate the maternal risk from pregnancy. For each patient, we determine both a New York Heart Association (NYHA) functional class and a World Health Organization (WHO) score.
The NYHA functional class is a classification system based on symptoms. The categories are as follows:
No limitation of physical activity. Ordinary physical activity does not cause undue fatigue, palpitation, or dyspnea (shortness of breath).
Slight limitation of physical activity. Comfortable at rest. Ordinary physical activity results in fatigue, palpitation, or dyspnea.
Marked limitation of physical activity. Comfortable at rest. Less than ordinary activity causes fatigue, palpitation, or dyspnea.
Unable to carry on any physical activity without discomfort. Symptoms of heart failure at rest. If any physical activity is undertaken, discomfort increases.
In and of itself, the NYHA system is not designed for risk stratification, but patients with a worse functional class generally have a worse outcome with regard to both morbidity and mortality regardless of the degree of left ventricular (LV) function.
The WHO risk score can be used to place patients into one of four risk categories based on their cardiac diagnosis. The risk score is outlined in Table 24.1 .
Score | Description |
---|---|
I | No increase in maternal mortality; small or no increase in morbidity |
II | Small increase in maternal mortality or moderate increase in morbidity |
III | Significantly increased risk of maternal mortality or severe morbidity |
IV | High risk of maternal mortality; pregnancy contraindicated |
Pulmonic stenosis
Patent ductus arteriosus
Mitral valve prolapse
Repaired simple defects such as atrial septal defect (ASD) or ventricular septal defect (VSD)
Premature atrial or premature ventricular beats
Unoperated ASD or VSD
Repaired tetralogy of Fallot
Most arrhythmias
Mild left ventricular dysfunction (LVD)
Hypertrophic cardiomyopathy
Marfan syndrome without aortic dilation
Repaired coarctation
Mechanical valve
Systemic right ventricle
Fontan circulation
Cyanotic disease unrepaired
Other complex congenital diseases
Aortic dilation (40–45 mm) with Marfan syndrome
Aortic dilation (45–50 mm) with a bicuspid valve
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