Anovulatory Endometrium with Persistent Follicle


D efinition —Alterations in the endometrium due to lack of ovulation and estrogenic effects of a persistent follicle.

Clinical Features

Epidemiology

  • Most commonly seen at or around menopause with failed ovulation and persistent follicle.

  • Common in polycystic ovarian syndrome (PCOS).

  • Abnormal uterine bleeding in the fourth or fifth decade is the most common presenting sign.

  • Can be mimicked by excessive estrogen administration post menopause.

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