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D efinition —Alterations in the endometrium due to lack of ovulation and estrogenic effects of a persistent follicle.
Most commonly seen at or around menopause with failed ovulation and persistent follicle.
Common in polycystic ovarian syndrome (PCOS).
Abnormal uterine bleeding in the fourth or fifth decade is the most common presenting sign.
Can be mimicked by excessive estrogen administration post menopause.
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