Physical Address
304 North Cardinal St.
Dorchester Center, MA 02124
Anal Intraepithelial Neoplasia II and III
D efinition —A high-grade, human papillomavirus (HPV)–associated, in situ lesion of the squamous anal mucosa.
Clinical Features
Epidemiology
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Associated with oncogenic HPV types (16 and 18).
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Increased risk with HPV, human immunodeficiency virus (HIV), anal intercourse, and multiple sexual partners.
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