Adenosquamous Carcinoma


D efinition —An aggressive variant of squamous cell carcinoma with conspicuous glandular differentiation.

Clinical Features

Epidemiology

  • Uncommon.

  • Mean age at diagnosis is 65 to 70 years.

  • Associated with chronic vulvar inflammatory disease.

  • Human papillomavirus (HPV) link is unclear but likely when coexisting with basaloid carcinomas.

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