Adenosarcoma of the Endometrium


D efinition A low-grade stromal malignancy of the uterus with preservation of the normal resident endometrial epithelium.

Clinical Features

Epidemiology

  • Most cases occur in postmenopausal women in their 60s, but a wide age range has been reported (teenagers to centenarians).

  • Tamoxifen therapy for breast cancer, as well as prolonged hyperestroginism (either exogenous or endogenous), has been linked to endometrial malignancy, including adenosarcoma.

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