Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE)


History of Present Illness

A 21-year-old college student was studying for finals in May and noticed a sudden decrease in vision in both eyes (OU). He had never experienced visual problems before and recently finished studying for the Medical College Admission Test (MCAT), so he wondered whether his symptoms were the result of stress. He is athletic and on the college basketball team.

Exam
OD OS
Visual acuity 20/80 20/100
Intraocular pressure (IOP) (mm Hg) 10 11
Sclera/conjunctiva Clear. No injection Clear. No injection
Cornea Clear Clear
Anterior chamber (AC) No cell or flare No cell or flare
Iris Normal Normal
Lens Clear Clear
Vitreous cavity No vitreous cells No vitreous cells
Retina/optic nerve Multiple yellowish, flat, creamy-colored placoid lesions in the posterior pole ( Fig. 32.1 ). Normal optic nerve Retinal lesions similar to those OD

Fig. 32.1, Multiple yellow, creamy-colored placoid lesions, flat in posterior pole, OD.

Questions to Ask

  • Have you had pain, redness, or floaters in either eye?

  • Have you had any illness within the past 6 to 8 weeks?

  • Did you experience transient hearing loss at the time of the flu?

He denies a history of pain, redness, or floaters in either eye. However, about 4 weeks ago he had the flu but has improved considerably. He had meningismus (stiff neck), slight hearing impairment, and occasional headaches while ill. However, they have almost totally resolved.

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