Physical Address
304 North Cardinal St.
Dorchester Center, MA 02124
Acute abdominal diseases frequently have atypical presentations in geriatric patients. Patients with intraabdominal sepsis may not have a fever or elevated white cell count, and conditions usually associated with abdominal pain (e.g., cholecystitis, pyelonephritis) may present as generalized sepsis without localizing signs.
When performing emergency computed tomography (CT) on geriatric patients, scanning with the highest pitch available can be desirable, and weight-based contrast dosing is recommended.
Gallstone ileus, colonic volvulus, stercoral colitis, and Ogilvie syndrome are rarely seen causes of bowel dilatation in younger patients but are not uncommon in this age group.
Geriatric patients are at increased risk of acute mesenteric ischemia, and if there is any clinical suspicion of ischemia, a biphasic CT protocol is recommended. Many of the earliest signs of ischemia (embolus, thrombosis, or vascular signs of nonocclusive ischemia) are only well seen on CT mesenteric angiography.
The investigation of acute illnesses in geriatric patients (those aged ≥65 years) poses a number of unique challenges. These patients more frequently present with atypical symptoms for a given condition, can delay seeking medical care (which allows for more advanced or multisystem disease upon presentation), and often have other medical conditions and multiple prescription medications, which can confound diagnosis or compound the impact of an illness. Geriatric patients are less likely to manifest fever and leukocytosis. A number of normal anatomic variants that occur with age can mimic disease processes on diagnostic imaging. These factors combine to result in reduced diagnostic accuracy for geriatric emergency patients, increased morbidity and mortality, and increased time in the emergency department (ED) until a diagnosis is made. ,
While radiography, ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI) all play roles in evaluating the emergency patient, there is evidence that the early use of CT in particular leads to a significant alteration in patient diagnosis and management, as well as time to patient disposition. Conventional radiography still has a role to play in the rapid identification of free intraperitoneal air, exclusion of a pulmonary process as the cause of upper abdominal pain, and evaluation for bowel obstruction, but CT is increasingly recognized as the primary diagnostic modality for geriatric patients with an acute abdomen. The assessment of right upper quadrant pain may still begin with US to assess for gallbladder pathology or biliary dilatation, and US can also exclude obstructive uropathy in the elderly patient presenting with acute kidney injury. MRI plays a much more limited role in these patients, primarily when biliary dilatation has been identified and choledocholithiasis is to be excluded.
This chapter will begin by discussing special considerations in the acquisition of CT and MRI abdominal studies unique to geriatric patients, as well as the use of iodinated contrast material in this population. Following this, anatomic variations and unique pathologies that develop with age will be addressed on a system-by-system basis.
CT is ideally suited for imaging elderly patients who may have limited breath-holding capacity, or who may have difficulty lying supine and still. The use of standard CT protocols may not be ideal for this group of patients, however, and it is worth developing a specialized approach for them.
The key parameter to consider in this group is scan time, in order to obtain images that preserve spatial resolution and are free of artifacts. It is thus desirable to scan with a higher pitch than one might use for a routine outpatient exam, recognizing that the reduction in motion artifact will usually far outweigh any theoretical reduction in image quality due to less redundant data sampling. In fact, it is rare to appreciate a significant difference in quality with modern scanners until above a pitch of 1.5. Many standard preinstalled vendor protocols will have the pitch set to a value of less than 1 in order to maximize image quality, whereas a pitch of 1 or more would be more appropriate for older emergency patients. The maximum pitch that could be deemed acceptable will be scanner dependent. While higher-pitch scans can be associated with a lower signal-to-noise ratio (for a static tube output, fewer photons will be able to penetrate the patient at each slice level as the patient moves more rapidly through the gantry), geriatric patients typically have a lower body mass index, and this is rarely a problem in practice. A higher-pitch technique also has the advantage of an overall lower radiation dose. A recent study evaluating the use of a pitch of 1.5 for emergency thoracoabdominal CT found a reduction in overall motion artifacts with no significant effect on image quality otherwise when scanning unconscious patients using single-source CT. A much higher pitch still can be utilized with dual-source CT, because each tube-and-detector combination can acquire 90 degrees of data simultaneously. A study of second-generation dual-source CT using pitch values of 2.1 to 2.5 allowed for the diagnostic assessment of the diaphragm free of motion artifact in more than 99% of blunt trauma patients, and third-generation scanners can reach a pitch of 3.2. Image noise will eventually become a limiting factor when the maximum pitch is approached, and additionally, if using both tubes simultaneously in a dual-tube system to achieve an ultrafast pitch, one must be aware of potential limitations on the field of view of the scan depending on the generation (33–35.6 cm for second- and third-generation systems). For both single- and dual-tube systems, the use of most dual-energy techniques across vendors is generally associated with a reduction in the maximum allowable pitch, and unless there is a specific use case in mind for a dual energy acquisition, this downside is often enough to avoid dual-energy scans in geriatric patients.
If using software that automatically selects an appropriate kVp based on the CT topogram, radiologists should be aware that levels of 80 to 100 kVp may be selected with smaller geriatric patients. While increased tube output will attempt to compensate for the lower photon energy level with increased photon flux (mA) and largely maintain signal-to-noise, the lower mean energy level of the photons will be closer to the k-edge of iodine and result in increased beam attenuation by iodinated contrast ( Fig. 9.1 ). This has definite advantages, in that the vasculature will be brighter and easier to assess (particularly smaller vessels), but also the disadvantage that at standard window/level (W/L) settings many solid organs will be too bright to optimally assess for parenchymal abnormalities without manual W/L adjustment. Beam hardening artifacts will also be more pronounced, and it may be advantageous to manually select a higher kVp if surgical hardware is identified on the topogram.
While MRI can be a valuable modality in scanning patients with a contraindication to iodinated contrast, in the elderly it may be still preferable to perform a noncontrast CT due to the challenges posed by motion artifact. One area where MRI is often unavoidable is in the exclusion of choledocholithiasis. Single-shot fast-spin echo techniques are extremely valuable in this case, as they are performed in single-slice acquisitions, and image quality is often satisfactory even when a patient is free breathing. Following thick (7–8 mm) and thin (3–4 mm) stack acquisitions in the axial and coronal planes, three-dimensional (3D) magnetic resonance cholangiopancreatography (MRCP) is acquired. Breath-holding 3D fast/turbo spin echo techniques usually require longer breath holds than an elderly patient can maintain, unless newer compressed sensing methods are used to heavily accelerate the acquisition, and respiratory triggering using a navigator echo on the diaphragm is generally advised for the 3D MRCP acquisition. In the event postcontrast imaging is felt to be necessary, scan time can be reduced to accommodate for breath-holding capacity by reducing the acquisition matrix or by increasing the parallel imaging factor. Newer scanners also offer novel T1-weighted 3D spoiled gradient echo sequences that utilize compressed sensing for acceleration to the point where a diagnostic free-breathing acquisition is possible, or radial stack-of-stars k-space acquisition, either of which would be preferable for challenging patients.
Become a Clinical Tree membership for Full access and enjoy Unlimited articles
If you are a member. Log in here