7 Laboratory Information System Providers Leading the Market Today

Laboratories rely on their information systems more than ever. The amount of data moving through a modern lab has grown in both volume and complexity, and the demand for faster, more reliable results continues to rise. A strong LIS helps manage that pressure by organizing specimens, maintaining accurate patient records, supporting regulatory compliance and creating a workflow that stays steady even when the caseload spikes.

Several LIS providers have emerged as leaders in this space. Each brings different strengths, and many serve different types of laboratories, from small specialty practices to large health systems with multiple locations. Below is a look at the LIS vendors most widely recognized today.

NovoPath

NovoPath has built its reputation around serving anatomic pathology laboratories with a system designed to match the pace and complexity of modern diagnostics. The platform focuses on keeping the entire workflow connected, from specimen accessioning to final report creation. Pathologists often point to the system’s organization, flexibility and ability to support both traditional and digital environments.

Many labs choose NovoPath because it adapts well to high throughput work, handles complex case structures and offers tools that allow teams to collaborate easily. It also fits comfortably into digital pathology workflows, making it a strong choice for groups transitioning into more modern diagnostic methods.

Sunquest PowerPath

Sunquest’s PowerPath has long been a familiar presence in hospital and reference lab settings. Its architecture is designed for large operations that need stability and the ability to scale across departments or multiple lab sites.

PowerPath is known for strong data structure, dependable reporting features and the ability to integrate into enterprise environments where many systems need to communicate. Labs with heavy volumes or complex organizational needs often consider it for its reliability and established history in pathology.

Cerner CoPath Plus

CoPath Plus is widely used in hospital pathology departments and academic medical centers. It offers structured reporting, detailed case management tools and a framework that supports a broad range of specimen types.

One of CoPath’s strengths is its compatibility with large health networks. Many hospitals already using Cerner’s electronic health record find that CoPath fits well into that ecosystem. The platform remains a steady option for institutions that prioritize uniform workflows across multiple clinical disciplines.

Epic Beaker

Epic Beaker is often selected by organizations that want their LIS tied directly to the rest of the patient’s electronic medical record. Because Beaker is part of the Epic ecosystem, it creates a unified environment where clinicians, pathologists and other specialists can work from the same source of information.

Beaker has grown steadily in its support for anatomic pathology. Health systems looking to streamline their infrastructure often choose it because of its strong integration capabilities and its ability to reduce the number of separate systems staff need to use.

Orchard Software

Orchard Software is common among community hospitals, regional labs and specialty clinics. Its systems are known for being approachable and easier to implement than some of the larger, enterprise-focused LIS platforms.

Many smaller laboratories prefer Orchard because the workflow is intuitive, support is accessible and the system can be configured without heavy IT overhead. As these labs grow or expand their services, Orchard’s flexibility becomes an advantage.

LabWare

LabWare has a strong presence in clinical laboratories, large networks and environments that depend heavily on automation. Its system is highly configurable, allowing organizations to build workflows tailored to their needs.

The platform tends to appeal to institutions with complex or specialized testing requirements. As digital tools and imaging become more common, LabWare continues to evolve alongside them, offering the infrastructure needed to organize data at scale.

Clinisys (formerly Sunquest/Clinisys suite)

Clinisys provides a broad portfolio of laboratory solutions across numerous diagnostic areas. Many public health and environmental labs rely on the company’s products, and it remains a recognizable name in large scale laboratory operations.

The platform supports structured data management, cross-lab connectivity and detailed reporting features. It is frequently chosen by institutions that operate across multiple facilities or need to coordinate results at a regional or statewide level.

The broader landscape

The LIS market continues to evolve as laboratories adopt digital pathology, remote workflows and new diagnostic technologies. The best LIS software is expected to do more than track specimens. It must support collaboration, integrate with imaging systems, manage data seamlessly and maintain stability under heavy workloads.

The vendors listed above represent the companies most often recognized for delivering those capabilities. Each has carved out its own space in the industry, and each offers something different depending on the size, specialty and goals of the laboratory.

While the systems vary in design and approach, they all reflect the same trend. Laboratories need tools that can keep up with rising demand, growing data requirements and more complex diagnostic expectations. The LIS providers leading the market today are the ones building toward that future, giving laboratories a stronger foundation for accuracy, efficiency and high quality patient care.