Lymph Node Overview


Lymph Nodes Differential Diagnosis
Inflammatory Infectious Regional metastases
Reactive nodes Viral upper respiratory infection Squamous cell carcinoma
Castleman disease Tuberculosis NHL
Kimura disease Atypical Mycobacterium species Melanoma
Kikuchi disease Cat-scratch disease Salivary neoplasms
Rosai-Dorfman disease HIV adenopathy Thyroid carcinoma
Inflammatory pseudotumor Malignant primary tumor Lung cancer
Hodgkin lymphoma
Non-Hodgkin lymphoma (NHL) Systemic metastases

Summary Thoughts: Cervical Nodes

Cervical lymph nodes can be classified based on anatomic distribution or surgical levels used for neck dissection.

The key decision when assessing a lymph node is deciding whether it is abnormal . Traditionally, size criteria have been employed, but a multifactorial approach (size, homogeneity, morphology, enhancement, and borders) is more useful.

If a lymph node appears abnormal, one must decide whether it harbors inflammation (reactive), infection (suppurative), or tumor [usually squamous cell carcinoma (SCCa)]. This distinction is often quite difficult, especially with uncommon inflammatory diseases.

It is important for radiologists to understand the typical patterns of nodal spread of disease. Particular attention must be paid to subclinical lymph nodes (e.g., retropharyngeal).

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