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Mucinous Tumors with Mural Nodules
D efinition — Mucinous tumors containing nodular foci in the cyst wall of altered mesenchymal and/or epithelial differentiation.
Clinical Features
Epidemiology
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Extremely uncommon; tendency toward women in the fifth and sixth decades.
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Associated with both borderline and malignant mucinous tumors.
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Etiology is unclear; however, one recent paper noted different codon 12 k-ras mutations in a mucinous tumor and its mural nodule, suggesting that both may have originated in a mucinous precursor cell followed by clonal divergence.
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