Serous Cancer Precursors


D efinition Epithelial proliferations with evidence of p53 mutations that do not fulfill the criteria for intramucosal carcinoma.

Clinical Features

Epidemiology

  • These lesions are rare and occur around menopause.

  • Occasionally seen in endometrial polyps.

  • Link between p53 positive epithelium with minimal atypia and cancer risk (of subsequent serous cancer) unknown.

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