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D efinition —A malignant germ cell tumor with endodermal sinus or vitelline differentiation.
The majority of patients are in their teens or twenties, although cases commonly occur in the first and fourth decades of life as well. The mean age is 19 years.
Yolk sac tumors are the second most common malignant germ cell tumor (dysgerminoma is the most common) but are relatively rare overall.
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