Yolk Sac Tumor


D efinition —A malignant germ cell tumor with endodermal sinus or vitelline differentiation.

Clinical Features

Epidemiology

  • The majority of patients are in their teens or twenties, although cases commonly occur in the first and fourth decades of life as well. The mean age is 19 years.

  • Yolk sac tumors are the second most common malignant germ cell tumor (dysgerminoma is the most common) but are relatively rare overall.

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