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Bleeding from a gastrointestinal (GI) source proximal to the ligament of Treitz (i.e., from the esophagus, stomach, or duodenum).
It is a thin, suspensory muscle that extends from the left crus of the diaphragm to the junction of the duodenum and jejunum. It is named for the Austrian physician Wenzel Treitz.
Peptic ulcer disease (PUD) is the most common cause of UGIB. Esophageal and gastric varices and esophagitis are the next most common.
Upper GI cancers, vascular malformations, Mallory-Weiss tears, and Dieulafoy’s lesions.
A tortuous, submucosal artery that protrudes through the mucosa and can cause massive UGIB. It is most commonly found in the gastric fundus, but other locations throughout the GI tract have been described. It is named after the French surgeon Paul Georges Dieulafoy.
Aortoenteric fistula and hemosuccus pancreaticus.
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