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Introduction Definition Pregnancy loss (PL) refers to the spontaneous demise of a pregnancy before reaching viability. Definitions for recurrent pregnancy loss (RPL) vary between two and three losses, and whether confirmation by ultrasonography or histopathology is required. , A clinical…
Key points Pregnancy loss affects approximately 10% to 30% of all clinically recognized pregnancies, with nearly 80% occurring in the first trimester. The majority of pregnancy losses are sporadic and result from genetic causes that are greatly influenced by maternal…