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Key Points Cytomegalovirus (CMV) can cause both primary and nonprimary infections. Around 50% of the pregnant women are seronegative; 1% will develop primary infection during pregnancy. Prenatal diagnosis relies on CMV polymerase chain reaction (PCR) in amniotic fluid (AF) sampled…

Introduction Viral infections are a concern to practitioners in prenatal diagnosis, particularly in the interpretation of an abnormal fetal ultrasound examination. It must be emphasized that the risks of transplacental transmission and fetal damage are pathogen- and gestation-specific. An optimal…