William R. Macon MD Archives

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Mature T-Cell and Natural Killer–Cell Leukemias

■ Introduction The mature T-cell and natural killer (NK)-cell leukemias form a heterogeneous group of diseases with diverse etiologies and markedly varied clinical behavior. When applied to T cells, the term mature or peripheral is often used to describe nonblastic…

Peripheral T-Cell Lymphomas

■ Introduction Peripheral T-cell lymphomas (PTCLs) are much less common than B-cell lymphomas, and they constitute approximately 10% of non-Hodgkin lymphomas (NHLs) in the United States and Europe. Derived from post-thymic T cells, PTCLs generally arise in lymphoid tissues ”peripheral”…