Overview of K + Distribution and Excretion–Internal and External Balance As the most abundant cation in intracellular fluid, K + plays an important role in a variety of cell functions. High K + concentration in cells and low K +…
Renal epithelial transport depends on the coordinated function of potassium channels with ion transporters (co-transporters, channels, and exchangers) and ion pumps in apical and basolateral membranes of distinct cell types along the nephron of the mammalian kidney. Potassium (K +…
In this chapter we review the transport of ions by the loop of Henle, distal convoluted tubule, the connecting tubule, and the collecting duct. We will place special emphasis on the cellular and molecular mechanisms responsible for Na + transport…