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INTRODUCTION The skin is a complex organ that is essential for all forms of mammalian life. It may be viewed as a double-layered sheath, cushioned by the underlying subcutaneous adipose tissue, that covers the entire surface of the body. The…
Key Points The incidence of melanoma continues to increase at epidemic proportions. Warning signs for melanoma include lesion asymmetry, border irregularity, color variation, diameter greater than 6 mm, and evolving changes. A subset of cancers—such as nodular, amelanotic, and desmoplastic melanoma—lack…