Leukocytosis is an elevation in the total leukocyte or white blood cell (WBC) count that is 2 SD above the mean for age (see Chapter 748 ). It is most often caused by elevated numbers of neutrophils (i.e., neutrophilia), although…
Leukopenia refers to an abnormally low number of white blood cells (WBCs) in the circulating blood secondary to a paucity of lymphocytes, granulocytes, or both. Because there are marked developmental changes in normal values for WBC counts during childhood (see…
Abstract Background Over the last six decades, our understanding of human immunology, coupled with our ability to interrogate the immune system in detail, has gone through a period of rapid evolution. From the early pioneers of immunology, Sir Peter Medawar…