Phagocytic leukocytes are an essential component of the innate immune system that has evolved to rapidly respond to the presence of invading bacteria, fungi, and parasites. This first line of host defense also includes natural killer (NK) lymphocytes, complement, and…
Neutrophils are the first line of defense against microbial invasion. They arrive at the site of inflammation during the critical 2-4 hr after microbial invasion to contain the infection and prevent hematogenous dissemination. This well-orchestrated process is one of the most…
The Phagocytic Inflammatory Response The phagocyte system includes both granulocytes (neutrophils, eosinophils, and basophils) and mononuclear phagocytes (monocytes and tissue macrophages). Neutrophils and mononuclear phagocytes share primary functions, including the defining properties of large-particle ingestion and microbial killing. Phagocytes participate…
Phagocytic leukocytes are an essential component of the innate immune system that has evolved to rapidly respond to the presence of invading bacteria, fungi, and parasites. This first line of host defense also includes natural killer (NK) lymphocytes, complement, and…