Tag Theresa Nester MD

Transfused blood products may have effects on recipient immunity. Broadly, these effects have been called transfusion-related immunomodulation (TRIM). Some TRIM effects are generally accepted, while others are a matter of debate. The TRIM effects can be categorized as beneficial or…

Leukocytes (white blood cells [WBCs]) remain in red blood cell (RBC) and platelet (PLT) components after simple component preparation. Residual leukocytes have the potential to cause harmful effects in the transfusion recipient including febrile nonhemolytic transfusion reactions (FNHTRs), HLA alloimmunization,…