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Why Cell-Free DNA-Based Noninvasive Prenatal Testing for Fetal Chromosome Anomalies Is Not Diagnostic
Introduction Since the commercial introduction of cfDNA-based prenatal tests in 2011, a plethora of studies with designs of proof of concept, validation, case reports, large cohort studies, and meta-analyses have been published. Although cfDNA-based prenatal screening for trisomy 21, 18,…