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Retarded skeletal maturation Chronic ill-health 1. Congenital heart disease —particularly cyanotic. 2. Renal failure. 3. Inflammatory bowel disease * . 4. Malnutrition. 5. Rickets * . 6. Maternal deprivation. Endocrine disorders 1. Hypothyroidism —severe retardation (≥5 standard deviations below the…