Steven H. Swerdlow Archives

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Iatrogenic Immunodeficiency-Associated Lymphoproliferative Disorders

Definition Lymphoproliferative disorders (LPDs) associated with iatrogenic immunodeficiency constitute a spectrum of lymphoid or plasmacytic proliferations, including a major subset that occurs after solid organ, stem cell, or bone marrow transplantation (post-transplant lymphoproliferative disorders [PTLDs]). A smaller number of cases…

Principles of Classification of Lymphoid Neoplasms

Historical Background The classification of lymphoid neoplasms used in this text is the one published by the World Health Organization (WHO) in WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues . Initially published in 2008, the WHO's fourth edition…

Hematolymphoid Tumors of the Breast

Introduction Breast hematological malignancies are rare. Breast lymphoma represents less than 1% of all malignant breast tumors and accounts for only 1% to 2% of extranodal lymphomas. The vast majority of primary breast lymphomas (PBLs) are non-Hodgkin’s lymphomas (NHLs). A…