Stergios J. Moschos Archives

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Brain Metastases from Cutaneous Melanoma: Biology and its Implications for More Rational Therapeutic Approaches

Introduction Cutaneous melanoma is the fifth and seventh most frequently diagnosed cancer in the United States in men and women, respectively, for 2014 ( ). In other countries, such as Australia, cutaneous melanoma has reached epidemic proportions. Although it is…

Adjuvant Therapy for Cutaneous Melanoma

Key Points Chemotherapy regimens, non-specific immunostimulants and vaccines alone have failed to show any survival benefit in the adjuvant setting. High-dose interferon-α2b is the only approved drug shown to improve relapse-free and overall survival in large multi-institutional randomized controlled trials…