Stephanie M. Boyd Archives

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Pathophysiologically based management of pulmonary hypertension of the newborn

Key points Acute pulmonary hypertension (aPH), classically referred to as persistent pulmonary hypertension of the newborn (PPHN) when occurring during the perinatal transition period, is characterized by failure of the normal postnatal decline in pulmonary vascular resistance (PVR). Elevated pulmonary…

Pathophysiology-based management of the hemodynamically significant patent ductus arteriosus in the very preterm neonate

Key points The simplistic “treat all or treat none” approach to management of a patent ductus arteriosus (PDA) has been increasingly challenged in recent years as the variation in clinical and hemodynamic presentation has been realized. Spontaneous closure rates, poor…