Shelley M. Lawrence Archives

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KEY POINTS 1. The fetal-neonatal immune system becomes activated at birth to play a role in host defense and eliminate environmental pathogens but also to tolerate self-antigens, nutrients, and commensals. 2. The innate immune system is comprised of neutrophils, the…

Neutrophil Granulopoiesis and Homeostasis

Introduction From their initial emergence in the yolk sac at the beginning stages of embryogenesis to their vast proliferation in the bone marrow at the end of term gestation, the differentiation of the pluripotent hematopoietic stem cell into a mature,…

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Neonatal Immunity

Neutrophil Granulopoiesis and Homeostasis