Tag Shaun Greene

Antidepressant drugs

Essentials 1 Tricyclic antidepressant (TCA) overdose is associated with severe cardiovascular toxicity, seizures, coma and death. 2 Sodium bicarbonate is the specific treatment of TCA cardiotoxicity. 3 Selective serotonin reuptake inhibitors (SSRIs) produce mild clinical effects in overdose; however very…