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Tag Seth J. Orlow

Melanocyte Biology

Key features ▪ The major determinant of normal skin color is the activity of melanocytes, i.e. the quantity and quality of pigment production, not the density of melanocytes ▪ Melanocytes contain a unique intracytoplasmic organelle, the melanosome, which is the…

Congenital Melanocytic Nevi

Key Points Congenital melanocytic nevi (CMN) can have medical, cosmetic, and psychological consequences. The natural history of CMN may be dynamic and can include development of erosions and proliferative nodules during infancy, changes in pigmentation and topography, neurotization, and spontaneous…