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Before the era of arterial reconstruction, lower extremity ischemic ulcers regularly progressed to gangrene and limb loss. Lumbar sympathectomy was first used to treat this condition in the 1920s by Diez in Buenos Aires and Adson and Brown at the…
Introduction Outcome measures play an important role in the field of dermatology, both in routine clinical practice and in clinical research trials. In clinical settings, robust outcome measures serve to classify disease severity, which can direct treatment choice. Outcome measures…