Abstract Background A subset of hemostatic disorders are due to an imbalance in coagulation or fibrinolysis. Disorders of coagulation or fibrinolysis can be either inherited (e.g., hemophilia A) or acquired (e.g., liver disease), and the clinical presentation is typically either…
Abstract Primary hemostasis is characterized by vascular contraction, platelet adhesion, and formation of a platelet thrombus. It begins immediately after endothelial disruption with platelets and von Willebrand factor (VWF) being the key components in the initiation of hemostatic process. This…
Abstract Background Hemostasis is a physiologic process involving platelets, coagulation and fibrinolysis proteins, and blood vessels that maintain blood in the fluid state under normal conditions but rapidly form a blood clot at sites of injury. Intact endothelial cells lining…