Brief introduction to immunotherapy Immune-based therapies have emerged as a promising modality in cancer treatment. These therapies use the body’s immune system to fight cancer by harnessing the antitumor properties of the host immune system to eliminate the cancer. Several…
Introduction Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most common side effects of cytotoxic chemotherapy and presents as a distal, symmetric polyneuropathy ( Table 28.1 ). Rates of CIPN depend on the agent being used but tend to occur…
Introduction Although neurofibromatosis and tuberous sclerosis comprise some of the most common inherited tumor syndromes in neuro-oncology, clinicians will encounter patients with other, less common syndromes who could present with a range of neurologic and extranervous manifestations of their disease.…
Introduction Tuberous sclerosis complex (TSC) is an autosomal dominant neurocutaneous condition characterized by a predisposition to hamartomas in the brain, heart, kidney, skin, eye, and other organs. TSC is the second most common neurogenetic tumor syndrome affecting approximately 1 in…